SORBS2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19081-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19081-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19081-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19081-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
SORBS2
Background:
Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
124 kDa
Concentration:
1.02 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:150-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human SORBS2
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
Arg binding protein 2;Arg-binding protein 2;Arg/Abl interacting protein 2;Arg/Abl interacting protein;Arg/Abl-interacting protein 2;ArgBP2;KIAA0777;PRO0618;sorbin and SH3 domain containing 2;Sorbin and SH3 domain-containing protein 2;Sorbin;Sorbs2;SRBS2
UNIProt ID:
O94875