ARIH2 Polyclonal Antibody

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Elabscience
Product Code: E-AB-19064
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-19064-20uL20uL£125.00
Quantity:
E-AB-19064-60uL60uL£172.00
Quantity:
E-AB-19064-120uL120uL£237.00
Quantity:
E-AB-19064-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human tonsil tissue using ARIH2 Polyclonal Antibody at dilution of 1:80(?200)
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Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ARIH2 Polyclonal Antibody at dilution of 1:80(?200)
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Immunohistochemistry of paraffin-embedded Human tonsil tissue using ARIH2 Polyclonal Antibody at dilution of 1:80(?200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ARIH2 Polyclonal Antibody at dilution of 1:80(?200)

Documents

Further Information

Abbreviation:
ARIH2
Background:
TRIAD1, also known as ARIH2 (ariadne homolog 2) or ARI2, is a 493 amino acid protein that contains one IBR-type zinc finger and two RING-type zinc fingers and belongs to the ariadne subfamily of RBR proteins. Localized to the nucleus, TRIAD1 interacts with UBE2L3 and is thought to act as an E3 ubiquitin-protein ligase, functioning to accept ubiquitin from E2 ubiquitin-conjugating enzymes and transfer the acquired ubiquitin residue to target substrates. TRIAD1 is subject to post-translational DNA damage-dependent phosphorylation, probably by ATM or ATR. The gene encoding TRIAD1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
58 kDa
Concentration:
1.38 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human ARIH2
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
HT005;all trans retinoic acid inducible RING finger;Ari 2;Ari-2;ARI2;ARI2;Ariadne 2;Ariadne 2 protein homolog;ariadne homolog 2 (Drosophila);ariadne homolog 2;Ariadne RBR E3 ubiquitin protein ligase 2;ARIH 2;Arih2;E3 ubiquitin protein ligase ARIH2;E3 ubiquitin-protein ligase ARIH2;protein ariadne 2 homolog;Protein ariadne-2 homolog;Triad 1;TRIAD1;Triad1 protein;UIP48
UNIProt ID:
O95376