FKBP4 Polyclonal Antibody

Elabscience
Product Code: E-AB-19050
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-19050-20uL20uL£125.00
Quantity:
E-AB-19050-60uL60uL£172.00
Quantity:
E-AB-19050-120uL120uL£237.00
Quantity:
E-AB-19050-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

1 / 2
Western blot analysis of 231 and HepG2 cell lysates  using FKBP4 Polyclonal Antibody at dilution of 1:900
2 / 2
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue  using FKBP4 Polyclonal Antibody at dilution of 1:65(?200)

Western blot analysis of 231 and HepG2 cell lysates  using FKBP4 Polyclonal Antibody at dilution of 1:900
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue  using FKBP4 Polyclonal Antibody at dilution of 1:65(?200)

Documents

Further Information

Abbreviation:
FKBP4
Background:
FKBP52 (FK506 binding protein 4) is a member of the immunophilin protein family that comprises intracellular protein effectors of immunosuppressive drugs,and it is known as a steroid receptor-associated protein. As a novel regulator of microtubule dynamics,FKBP52 is associated with the motor protein dynein and with the cytoskeleton during mitosis. FKBP52 is highly expressed in CNS regions susceptible to Alzheimer's,and plays a role in modulating toxicity of Abeta peptides. The protein can associate with the Tau function,and may help to decipher and modulate the events involved in Tau-induced neurodegeneration. In addition,FKBP52 is likely to play a role in growth and development of the male genitalia.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
52 kDa
Concentration:
1.14 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human FKBP4
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
51 kDa FK506-binding protein;52 kDa FK506 binding protein;52 kDa FK506-binding protein;52 kDa FKBP;59 kDa immunophilin;FK506 binding protein 4;FK506-binding protein 4;FKBP 4;FKBP 52;FKBP 59;FKBP-4;FKBP-52;FKBP4;FKBP4;FKBP51;FKBP52 protein;FKBP59;HBI;Hsp 56;HSP binding immunophilin;HSP-binding immunophilin;Hsp56;Immunophilin FKBP52;N-terminally processed;p52;p59;p59 protein;Peptidyl prolyl cis trans isomerase;Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidylprolyl cis trans isomerase;PPIase;PPIase FKBP4;Rotamase;T cell FK506 binding protein 59kD
UNIProt ID:
Q02790