IFT57 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19035-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19035-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19035-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19035-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
IFT57
Background:
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human IFT57
Purification method:
Antigen affinity purification
Target Synonym:
CDNA FLJ10147 fis clone HEMBA1003369;Dermal papilla derived protein 8;Dermal papilla-derived protein 8;DERP 8;DERP8;Esrrbl 1;Esrrbl1;ESRRBL1 protein;Estrogen related receptor beta like 1;Estrogen related receptor beta like protein 1;Estrogen-related receptor beta-like protein 1;FLJ10147;Hip1 Interacting protein;HIP1 interacting protein HIPPI;Hip1 protein interactor;HIP1-interacting protein;HIPPI;Huntingtin interacting protein 1 interacting protein;Huntingtin interacting protein 1 protein interactor;IFT 57;ift57;IFT57;Intraflagellar transport 57 homolog (Chlamydomonas);Intraflagellar transport 57 homolog;Intraflagellar transport protein 57 homolog;MHS4R2;Vestrogen related receptor beta like 1
UNIProt ID:
Q9NWB7