ACTL6B Polyclonal Antibody

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Elabscience
Product Code: E-AB-19033
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-19033-20uL20uL£125.00
Quantity:
E-AB-19033-60uL60uL£172.00
Quantity:
E-AB-19033-120uL120uL£237.00
Quantity:
E-AB-19033-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ACTL6B Polyclonal Antibody at dilution of 1:100(?200)
2 / 2
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using ACTL6B Polyclonal Antibody at dilution of 1:100(?200)
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Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ACTL6B Polyclonal Antibody at dilution of 1:100(?200)
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using ACTL6B Polyclonal Antibody at dilution of 1:100(?200)

Documents

Further Information

Abbreviation:
ACTL6B
Background:
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
47 kDa
Concentration:
1.74 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human ACTL6B
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
53 kDa BRG1 associated factor B;53 kDa BRG1-associated factor B;ACL 6B;ACL6B;ACL6B;Actin like 6;Actin like protein 6B;Actin like protein6B;Actin related protein;Actin related protein Baf53b;actin-like 6B;Actin-like protein 6B;Actin-related protein Baf53b;Actl 6;ACTL 6B;Actl6;ACTL6 B;Actl6b;Arp Na;ArpN a;ArpN alpha;ArpNa;ArpNalpha;Baf 53b;BAF53B;BRG1-associated factor 53B
UNIProt ID:
O94805