SF3B3 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19022-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19022-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19022-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19022-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
SF3B3
Background:
This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human SF3B3
Purification method:
Antigen affinity purification
Target Synonym:
KIAA0017;Pre mRNA splicing factor SF3b 130 kDa subunit;Pre-mRNA-splicing factor SF3b 130 kDa subunit;RSE1;SAP 130;SAP130;SF3b130;SF3B3;SF3B3_HUMAN;Spliceosome associated protein 130;Spliceosome-associated protein 130;Splicing factor 3b subunit 3 130kD;Splicing factor 3B subunit 3;STAF130
UNIProt ID:
Q15393