NIPBL Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-18915-20uL | 20uL | £125.00 |
Quantity:
| E-AB-18915-60uL | 60uL | £172.00 |
Quantity:
| E-AB-18915-120uL | 120uL | £237.00 |
Quantity:
| E-AB-18915-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
NIPBL
Background:
This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and cognitive disability. Two transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human NIPBL
Purification method:
Antigen affinity purification
Target Synonym:
CDLS;Colon tumor susceptibility 2;Delangin;DKFZp434L1319;FLJ11203;FLJ12597;FLJ13354;FLJ13648;FLJ44854;IDN 3;IDN 3 protein;IDN 3 protein isoform A;IDN 3 protein isoform B;IDN 3B;IDN3 B;IDN3 protein;IDN3 protein isoform A;IDN3 protein isoform B;IDN3B;Mis 4;Mis4;Nipbl;NIPBL;Nipped B homolog (Drosophila);Nipped B homolog;Nipped B like;Nipped B like protein;Nipped-B-like protein;Scc 2;SCC 2 homolog;Scc2;SCC2 homolog;Sister chromatid cohesion protein Mis4
UNIProt ID:
Q6KC79