ILF3 Polyclonal Antibody

Elabscience
Product Code: E-AB-18909
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-18909-20uL20uL£125.00
Quantity:
E-AB-18909-60uL60uL£172.00
Quantity:
E-AB-18909-120uL120uL£237.00
Quantity:
E-AB-18909-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue  using ILF3 Polyclonal Antibody at dilution of 1:60(?200)
2 / 2
Immunohistochemistry of paraffin-embedded Human breast cancer tissue  using ILF3 Polyclonal Antibody at dilution of 1:60(?200)

Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue  using ILF3 Polyclonal Antibody at dilution of 1:60(?200)
Immunohistochemistry of paraffin-embedded Human breast cancer tissue  using ILF3 Polyclonal Antibody at dilution of 1:60(?200)

Documents

Further Information

Abbreviation:
ILF3
Background:
This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.08 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human ILF3
Purification method:
Antigen affinity purification
Target Synonym:
CBTF;Double stranded RNA binding protein 76;Double-stranded RNA-binding protein 76;DRBF;DRBP76;ILF3;ILF3;Interleukin enhancer binding factor 3;Interleukin enhancer-binding factor 3;M phase phosphoprotein 4;M-phase phosphoprotein 4;MPHOSPH4;MPP4;NF AT 90;NF-AT-90;NF110;NF90;NFAR;Nuclear factor associated with dsRNA;Nuclear factor of activated T cells 90 kDa;Nuclear factor of activated T-cells 90 kDa;TCP80;Translational control protein 80
UNIProt ID:
Q12906