GSKIP Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-18894-20uL | 20uL | £125.00 |
Quantity:
| E-AB-18894-60uL | 60uL | £172.00 |
Quantity:
| E-AB-18894-120uL | 120uL | £237.00 |
Quantity:
| E-AB-18894-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
GSKIP
Background:
This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.96 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human GSKIP
Purification method:
Antigen affinity purification
Target Synonym:
C14ORF129;Chromosome 14 open reading frame 129 ;GSK3-beta interaction protein;GSK3beta interaction protein;GSKIP;GSKIP;MGC4945;UPF0279
UNIProt ID:
Q9P0R6