GTF2A2 Polyclonal Antibody
Code | Size | Price |
---|
E-AB-18882-20uL | 20uL | £125.00 |
Quantity:
E-AB-18882-60uL | 60uL | £172.00 |
Quantity:
E-AB-18882-120uL | 120uL | £237.00 |
Quantity:
E-AB-18882-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Images
Further Information
Abbreviation:
GTF2A2
Background:
Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972). The first step involves recognition of the TATA element by the TATA-binding subunit (TBP; MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF; MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]).
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.54 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human GTF2A2
Purification method:
Antigen affinity purification
Target Synonym:
General transcription factor IIA;General transcription factor IIA subunit 2;General transcription factor IIA; 2 (12kD subunit);General transcription factor IIA; 2; 12kDa;gtf2a2;HsT18745;T2AG;TF2A2;TFIIA 12;TFIIA;TFIIA gamma ;TFIIA p12 subunit;TFIIA-12;TFIIA-gamma;TFIIA12;TFIIAS;Transcription initiation factor IIA gamma chain;Transcription initiation factor IIA subunit 2
UNIProt ID:
P52657