HLA-DPB1 Polyclonal Antibody

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Elabscience
Product Code: E-AB-18805
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-18805-20uL20uL£125.00
Quantity:
E-AB-18805-60uL60uL£172.00
Quantity:
E-AB-18805-120uL120uL£237.00
Quantity:
E-AB-18805-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human tonsil tissue using HLA-DPB1 Polyclonal Antibody at dilution of 1:45(?200)
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Immunohistochemistry of paraffin-embedded Human tonsil tissue using HLA-DPB1 Polyclonal Antibody at dilution of 1:45(?200)

Documents

Further Information

Abbreviation:
HLA-DPB1
Background:
HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.78 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human HLA-DPB1
Purification method:
Antigen affinity purification
Target Synonym:
D6S221E;DMA;DMB;DP beta 1;DP beta 1 chain;DP(W4) beta chain;DPB 1;DPB1;DPB1;DRB;H2Ea;HLA class II histocompatibility antigen;HLA class II histocompatibility antigen DM beta chain ;HLA class II histocompatibility antigen; DP beta 1 chain;HLA class II histocompatibility antigen; DP(W4) beta chain;HLA DMB;HLA DP1A;HLA DPB1;HLA SB alpha chain;HLA-A;HLA-A histocompatibility type;HLA-DP;HLA-DP histocompatibility type; beta-1 subunit;HLA-DP1B;HLA-DPB;HLA-DPB1;HLADM;HLADP1B;HLASB;HLASB histocompatibility type;Human MHC class II HLA SB alpha;LA class II histocompatibility antigen DP alpha 1 chain;Major histocompatibility complex class II;Major histocompatibility complex class II DP alpha 1;Major histocompatibility complex class II DP beta 1;Major histocompatibility complex; class I; A;MHC class II antigen DMB;MHC class II antigen DPB1;MHC class II DP3 alpha;MHC class II DPA1;MHC class II HLA-DP-beta-1;MHC DPB1;MHC HLA DPB1;PLT1;Primed lymphocyte test 1;RING6;RING7
UNIProt ID:
P04440