ISCU Polyclonal Antibody
Code | Size | Price |
---|
E-AB-18785-20uL | 20uL | £125.00 |
Quantity:
E-AB-18785-60uL | 60uL | £172.00 |
Quantity:
E-AB-18785-120uL | 120uL | £237.00 |
Quantity:
E-AB-18785-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Images
Further Information
Abbreviation:
ISCU
Background:
This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
18 kDa
Concentration:
0.96 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human ISCU
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
2310020H20Rik;HML;hnifU;Iron sulfur cluster assembly enzyme ISCU mitochondrial;Iron sulfur cluster scaffold homolog (E. coli);Iron sulfur cluster scaffold homolog;Iron-sulfur cluster assembly enzyme ISCU;Iscu;IscU iron sulfur cluster scaffold homolog;ISCU;ISU2;MGC74517;mitochondrial;NIFU;NifU like N terminal domain containing;NifU like N terminal domain containing protein;NifU like protein;NifU-like N-terminal domain-containing protein;NifU-like protein;NIFUN;Nitrogen fixation cluster like;OTTHUMP00000238760;OTTHUMP00000238761;OTTHUMP00000238762;OTTHUMP00000238764;OTTHUMP00000238765
UNIProt ID:
Q9H1K1