C8orf4 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-18766-20uL | 20uL | £125.00 |
Quantity:
| E-AB-18766-60uL | 60uL | £172.00 |
Quantity:
| E-AB-18766-120uL | 120uL | £237.00 |
Quantity:
| E-AB-18766-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
C8orf4
Background:
This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.96 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human C8orf4
Purification method:
Antigen affinity purification
Target Synonym:
C8orf4;CH004;Chromosome 8 open reading frame 4;Human thyroid cancer 1;MGC22806;TC-1;TC1;Thyroid cancer protein 1;Uncharacterized protein C8orf4
UNIProt ID:
Q9NR00