TIMM8A Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-18755-20uL | 20uL | £125.00 |
Quantity:
| E-AB-18755-60uL | 60uL | £172.00 |
Quantity:
| E-AB-18755-120uL | 120uL | £237.00 |
Quantity:
| E-AB-18755-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
TIMM8A
Background:
This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.84 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human TIMM8A
Purification method:
Antigen affinity purification
Target Synonym:
DDP 1;DDP;DDP1;Deafness dystonia protein 1;Deafness/dystonia peptide;DFN 1;DFN1;MGC12262;Mitochondrial import inner membrane translocase subunit Tim8 A;MTS;TIM 8A;TIM8;TIM8A;TIM8A;TIMM 8A;timm8a;Translocase of inner mitochondrial membrane 8 homolog A;X linked deafness dystonia protein;X-linked deafness dystonia protein
UNIProt ID:
O60220