PFKM Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-18753-20uL | 20uL | £125.00 |
Quantity:
| E-AB-18753-60uL | 60uL | £172.00 |
Quantity:
| E-AB-18753-120uL | 120uL | £237.00 |
Quantity:
| E-AB-18753-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
PFKM
Background:
Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
85 kDa
Concentration:
1.02 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human PFKM
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
6 Phosphofructokinase Muscle Type;6-phosphofructokinase;6-phosphofructokinase muscle type;EC 2.7.1.1;EC 2.7.1.11;GSD7;K6PF;MGC8699;muscle type;PFK;muscle type;PFK-A;PFKA;PFKL;PFKM;PFKP;PFKX;Phosphofructo 1 Kinase Isozyme A;Phosphofructo-1-kinase isozyme A;Phosphofructokinase 1;Phosphofructokinase M;Phosphofructokinase;muscle;Phosphofructokinase;muscle type;Phosphofructokinase;polypeptide X;Phosphofructokinase-M;Phosphohexokinase
UNIProt ID:
P08237
References
- https://link.springer.com/article/10.1186/s12929-022-00855-6