CD86 Polyclonal Antibody

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Elabscience
Product Code: E-AB-18593
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-18593-20uL20uL£125.00
Quantity:
E-AB-18593-60uL60uL£172.00
Quantity:
E-AB-18593-120uL120uL£237.00
Quantity:
E-AB-18593-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of Human lymph gland tissue and Jurkat cell lysates using CD86 Polyclonal Antibody at dilution of 1:450
2 / 2
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CD86 Polyclonal Antibody at dilution of 1:30(?200)
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Western blot analysis of Human lymph gland tissue and Jurkat cell lysates using CD86 Polyclonal Antibody at dilution of 1:450
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CD86 Polyclonal Antibody at dilution of 1:30(?200)

Documents

Further Information

Abbreviation:
CD86
Background:
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
38 kDa
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human CD86
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
Activation B7-2 antigen 3;Activation B7-2 antigen;B-lymphocyte activation antigen B7-2 2;B-lymphocyte activation antigen B7-2;B7 2;B7;B7-2;B7.2;B70;B72 antigen;BU63;CD28 antigen ligand 2 2;CD28 antigen ligand 2;Cd28l2;CD28LG2;CD86;CD86 antigen;CD86 antigen;CD86 molecule;CD86;CLS1;CTLA-4 counter-receptor B7.2 2;3;CTLA-4 counter-receptor B7.2;Early T-cell costimulatory molecule 1;ETC-1;FUN 1;FUN-1;LAB72;Ly-58;Ly58;MB7;MB7-2;Membrane glycoprotein;MGC34413;T-lymphocyte activation antigen CD86;TS/A-2
UNIProt ID:
P42081

References

  • https://www.sciencedirect.com/science/article/pii/S1567576919322672
  • https://peerj.com/articles/8294/