C7 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-18574-20uL | 20uL | £125.00 |
Quantity:
| E-AB-18574-60uL | 60uL | £172.00 |
Quantity:
| E-AB-18574-120uL | 120uL | £237.00 |
Quantity:
| E-AB-18574-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
C7
Background:
This gene encodes a serum glycoprotein that forms a membrane attack complex together with complement components C5b, C6, C8, and C9 as part of the terminal complement pathway of the innate immune system. The protein encoded by this gene contains a cholesterol-dependent cytolysin/membrane attack complex/perforin-like (CDC/MACPF) domain and belongs to a large family of structurally related molecules that form pores involved in host immunity and bacterial pathogenesis. This protein initiates membrane attack complex formation by binding the C5b-C6 subcomplex and inserts into the phospholipid bilayer, serving as a membrane anchor. Mutations in this gene are associated with a rare disorder called C7 deficiency.
C7 (Complement C7) is a Protein Coding gene. Diseases associated with C7 include C7 Deficiency and Immunodeficiency Due To A Late Component Of Complement Deficiency. Among its related pathways are Complement Pathway and Innate Immune System. An important paralog of this gene is C6.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
94 kDa
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human C7
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
C7;CO7;complement component 7;Complement component C7
UNIProt ID:
P10643