COA7 Polyclonal Antibody
Code | Size | Price |
---|
E-AB-18566-20uL | 20uL | £125.00 |
Quantity:
E-AB-18566-60uL | 60uL | £172.00 |
Quantity:
E-AB-18566-120uL | 120uL | £237.00 |
Quantity:
E-AB-18566-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Images
Further Information
Abbreviation:
COA7
Background:
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. COA7 (cytochrome c oxidase assembly factor 7), also known as RESA1, SELRC1 or C1orf163, is a 231 amino acid mitochondrial protein that belongs to the hcp beta-lactamase family. Consisting of five Sel1-like repeats, COA7 may be associated with respiratory chain assembly. COA7 is encoded by a gene located on human chromosome 1p32.3. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene, which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
26 kDa
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Full length fusion protein
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
beta-lactamase hcp-like protein;C1orf163;Chromosome 1 open reading frame 163;FLJ12439;Hcp beta lactamase like protein C1orf163;Hypothetical protein LOC65260;RESA1;Sel1 repeat containing 1;sel1 repeat-containing protein 1
UNIProt ID:
Q96BR5