PHF21A Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-18538-20uL | 20uL | £125.00 |
Quantity:
| E-AB-18538-60uL | 60uL | £172.00 |
Quantity:
| E-AB-18538-120uL | 120uL | £237.00 |
Quantity:
| E-AB-18538-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
PHF21A
Background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. PHF21A (PHD finger protein 21A), also known as BRAF35-HDAC complex protein BHC80, is a 680 amino acid nuclear protein that contains one PHD-type zinc finger and one A.T hook DNA-binding domain, suggesting involvement in transcriptional regulation events. PHF21A is a component of the BHC complex, which is responsible for repressing transcription of neuron-specific genes in non-neuronal cells. The BHC complex acts as a chromatin modifier that deacetylates and demethylates specific sites on histones. PHF21A may act as a scaffold within the BHC complex. Predominantly expressed in brain, three isoforms of PHF21A exist as a result of alternative splicing events.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
75 kDa
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human PHF21A
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
BHC80a;BM-006;BRAF35-HDAC complex protein BHC80;BRAF35/HDAC2 complex (80 kDa);KIAA1696;PF21A;PHD finger protein 21A;PHF21A
UNIProt ID:
Q96BD5