ATXN3 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-18525-20uL | 20uL | £125.00 |
Quantity:
| E-AB-18525-60uL | 60uL | £172.00 |
Quantity:
| E-AB-18525-120uL | 120uL | £237.00 |
Quantity:
| E-AB-18525-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
ATXN3
Background:
Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.7 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human ATXN3
Purification method:
Antigen affinity purification
Target Synonym:
AT3;Ataxin 3;ataxin 3 variant h;ataxin 3 variant m;ataxin 3 variant ref;Ataxin-3;ATX3;ATX3;ATXN3;EC 3.4.22.;JOS;Josephin;Machado Joseph disease (spinocerebellar ataxia 3;olivopontocerebellar ataxia 3;autosomal dominant;ataxin 3);Machado Joseph disease;Machado Joseph disease protein 1;Machado-Joseph disease protein 1;Machado-Joseph disease protein 1 homolog;MJD;MJD gene;MJD1;Olivopontocerebellar ataxia 3;OTTHUMP00000221583;OTTHUMP00000221585;OTTHUMP00000221586;OTTHUMP00000221587;OTTHUMP00000231995;OTTHUMP00000231997;Rsca3;SCA3;SCA3 gene;Spinocerebellar ataxia type 3 protein
UNIProt ID:
P54252