UNC45B Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-18510-20uL | 20uL | £125.00 |
Quantity:
| E-AB-18510-60uL | 60uL | £172.00 |
Quantity:
| E-AB-18510-120uL | 120uL | £237.00 |
Quantity:
| E-AB-18510-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
UNC45B
Background:
This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
104/95 kDa
Concentration:
0.8 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human UNC45B
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
Cardiomyopathy associated 4 ;CMYA4 ;FLJ38610;MGC119540;MGC119541;OTTHUMP00000163855;Protein unc 45 homolog B;Protein unc-45 homolog B;SMUNC45;Striated muscle UNC45;UN45B;Unc 45 homolog B (C. elegans);Unc 45 homolog B;UNC 45B;UNC-45B;UNC45 ;UNC45B
UNIProt ID:
Q8IWX7