WDFY2 Polyclonal Antibody

Elabscience
Product Code: E-AB-18486
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-18486-20uL20uL£125.00
Quantity:
E-AB-18486-60uL60uL£172.00
Quantity:
E-AB-18486-120uL120uL£237.00
Quantity:
E-AB-18486-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

1 / 2
Western blot analysis of Mouse kidney tissue lysate  using WDFY2 Polyclonal Antibody at dilution of 1:350
2 / 2
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue  using WDFY2 Polyclonal Antibody at dilution of 1:40(?200)

Western blot analysis of Mouse kidney tissue lysate  using WDFY2 Polyclonal Antibody at dilution of 1:350
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue  using WDFY2 Polyclonal Antibody at dilution of 1:40(?200)

Documents

Further Information

Abbreviation:
WDFY2
Background:
WD repeat and FYVE domain-containing protein 2 (WDFY2), also known as WDF2 and ZFYVE22, is a 400 amino acid protein that localizes to a set of small endosomes that are found within 100 nm from the plasma membrane. Highly conserved between species, WDFY2 consists of one FYVE-type zinc finger and seven WD repeats. The FYVE domain is a cysteine-rich domain of about 70 amino acids. Its primary role is to target signal-transducing proteins to cell membranes through binding to the membrane lipid phosphatidylinositol-3-phosphate with high specificity. WD-repeats are generally found in clusters of seven. They have no intrinsic catalytic activity, but they serve as a platform for protein-protein interactions. WDFY2 is suspected to play a critical role in the endocytic pathway.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
45 kDa
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human WDFY2
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
PROF;Propeller-FYVE protein;RP11 147H23.1;WD repeat and FYVE domain containing 2;WD repeat and FYVE domain-containing protein 2;WD40 and FYVE domain containing 2;WD40- and FYVE domain-containing protein 2;WDF2;Wdfy2;WDFY2;ZFYVE22;Zinc finger FYVE domain-containing protein 22
UNIProt ID:
Q96P53