PRNP Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-18439-20uL | 20uL | £125.00 |
Quantity:
| E-AB-18439-60uL | 60uL | £172.00 |
Quantity:
| E-AB-18439-120uL | 120uL | £237.00 |
Quantity:
| E-AB-18439-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
PRNP
Background:
The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human PRNP
Purification method:
Antigen affinity purification
Target Synonym:
Alternative prion protein; major prion protein;AltPrP;ASCR;CD230;CD230 antigen;CJD;GSS;KURU;Major prion protein;p27 30;PRIO;Prion protein;Prion related protein;PRIP;PRNP;PrP;PrP27 30 ;PrP27-30;PrP33-35C;PrPC;PrPSc;Sinc
UNIProt ID:
P04156