GRAP Polyclonal Antibody
Code | Size | Price |
---|
E-AB-18391-20uL | 20uL | £125.00 |
Quantity:
E-AB-18391-60uL | 60uL | £172.00 |
Quantity:
E-AB-18391-120uL | 120uL | £237.00 |
Quantity:
E-AB-18391-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Images
Further Information
Abbreviation:
GRAP
Background:
This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.7 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Full length fusion protein
Purification method:
Antigen affinity purification
Target Synonym:
Grap;GRAP;GRB2 related adaptor protein;GRB2-related adapter protein;Growth factor receptor bound protein 2 related adaptor protein;MGC64880;OTTHUMP00000065766
UNIProt ID:
Q13588