ZNF486 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-18362-20uL | 20uL | £125.00 |
Quantity:
| E-AB-18362-60uL | 60uL | £172.00 |
Quantity:
| E-AB-18362-120uL | 120uL | £237.00 |
Quantity:
| E-AB-18362-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
ZNF486
Background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr?ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF486 (Zinc finger protein 486), also known as KRAB domain only protein 2, is a 216 amino acid nuclear protein that contains one KRAB domain and two C2H2-type zinc fingers. The gene encoding ZNF486 maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. May be involved in transcriptional regulation.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:250, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human ZNF486
Purification method:
Antigen affinity purification
Target Synonym:
KRAB box only protein 2 ;KRBO2 ;Zinc finger protein 486
UNIProt ID:
Q96H40