ATF6B Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-18330-20uL | 20uL | £125.00 |
Quantity:
| E-AB-18330-60uL | 60uL | £172.00 |
Quantity:
| E-AB-18330-120uL | 120uL | £237.00 |
Quantity:
| E-AB-18330-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
ATF6B
Background:
The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
77 kDa
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human ATF6B
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
ATF6B;CREBL1;G13;Cyclic AMP-dependent transcription factor ATF-6 beta;cAMP-dependent transcription factor ATF-6 beta;Activating transcription factor 6 beta;ATF6-beta;Protein G13;cAMP response element-binding protein-related protein;
UNIProt ID:
Q99941
References
- https://www.degruyter.com/view/journals/tjb/44/5/article-p599.xml