ZFAND5 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-18321-20uL | 20uL | £125.00 |
Quantity:
| E-AB-18321-60uL | 60uL | £172.00 |
Quantity:
| E-AB-18321-120uL | 120uL | £237.00 |
Quantity:
| E-AB-18321-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
ZFAND5
Background:
Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
23 kDa
Concentration:
1.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Immunogen:
Full length fusion protein
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
AN1-type zinc finger protein 5;ZA20D2;ZFAN5;Zfand5;ZFAND5A;zinc finger A20 domain containing 2 ;Zinc finger A20 domain containing protein 2 ;Zinc finger A20 domain-containing protein 2;zinc finger AN1 type domain 5;Zinc finger protein 216;ZNF216
UNIProt ID:
O76080