TPT1 Polyclonal Antibody

Elabscience
Product Code: E-AB-18294
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-18294-20uL20uL£125.00
Quantity:
E-AB-18294-60uL60uL£172.00
Quantity:
E-AB-18294-120uL120uL£237.00
Quantity:
E-AB-18294-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

1 / 2
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue  using TPT1 Polyclonal Antibody at dilution of 1:85(?200)
2 / 2
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue  using TPT1 Polyclonal Antibody at dilution of 1:85(?200)

Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue  using TPT1 Polyclonal Antibody at dilution of 1:85(?200)
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue  using TPT1 Polyclonal Antibody at dilution of 1:85(?200)

Documents

Further Information

Abbreviation:
TPT1
Background:
This gene encodes a protein that is a regulator of cellular growth and proliferation. Its mRNA is highly structured and contains an oligopyrimidine tract (5'-TOP) in its 5' untranslated region that functions to repress its translation under quiescent conditions. The encoded protein is involved in a variety of cellular pathways, including apoptosis, protein synthesis and cell division. It binds to and stabilizes microtubules, and removal of this protein through phosphorylation is required for progression through mitotic and meiotic cell divisions. This gene is known to play a role in carcinogenesis, and is upregulated in some cancer cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
20 kDa
Concentration:
1.6 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:45-1:300, ELISA 1:5000-1:10000
Immunogen:
Full length fusion protein
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
FLJ27337;Fortilin;Histamine releasing factor;Histamine-releasing factor;HRF;Immunoglobulin E-dependent;p02;p23;TCTP;TCTP;tpt1;Translationally controlled tumor protein;Translationally-controlled tumor protein;Tumor protein translationally controlled 1;tumor protein;translationally-controlled 1
UNIProt ID:
P13693

References

  • https://www.mdpi.com/1422-0067/20/9/2151