TGFBI Polyclonal Antibody

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Elabscience
Product Code: E-AB-18249
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-18249-20uL20uL£125.00
Quantity:
E-AB-18249-60uL60uL£172.00
Quantity:
E-AB-18249-120uL120uL£237.00
Quantity:
E-AB-18249-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of Rat liver tissue lysate using TGFBI Polyclonal Antibody at dilution of 1:850
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TGFBI Polyclonal Antibody at dilution of 1:60(?200)
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Western blot analysis of Rat liver tissue lysate using TGFBI Polyclonal Antibody at dilution of 1:850
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TGFBI Polyclonal Antibody at dilution of 1:60(?200)

Documents

Further Information

Abbreviation:
TGFBI
Background:
TGFBI,also named as BIGH3,Kerato-epithelin and RGD-CAP,binds to type I,II,and IV collagens. TGFBI is an adhesion protein which may play an important role in cell-collagen interactions. In cartilage,it may be involved in endochondral bone formation. TGFBI is an extracellular matrix adaptor protein,it has been reported to be differentially expressed in transformed tissues. TGFBI is a predictive factor of the response to chemotherapy,and suggest the use of TGFBI-derived peptides as possible therapeutic adjuvants for the enhancement of responses to chemotherapy. Defects in TGFBI are the cause of epithelial basement membrane corneal dystrophy (EBMD). Defects in TGFBI are the cause of corneal dystrophy Groenouw type 1 (CDGG1). Defects in TGFBI are the cause of corneal dystrophy lattice type 1 (CDL1). Defects in TGFBI are a cause of corneal dystrophy Thiel-Behnke type (CDTB). Defects in TGFBI are the cause of Reis-Buecklers corneal dystrophy (CDRB). Defects in TGFBI are the cause of lattice corneal dystrophy type 3A (CDL3A). Defects in TGFBI are the cause of Avellino corneal dystrophy (ACD).
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
75 kDa
Concentration:
1.02 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human TGFBI
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
>RGD containing collagen associated protein;AI181842;AI747162;Beta ig;Beta ig h3;Beta ig-h3;BGH3;Big h3;BIGH3;CDB1;CDG2;CDGG1;CSD;CSD1;CSD2;CSD3;EBMD;Kerato epithelin;Kerato-epithelin;LCD1;MGC150270;RGD CAP;RGD-CAP;RGD-containing collagen-associated protein;TGFBI;TGFBI transforming growth factor;beta induced;68kDa;Transforming growth factor beta induced protein ig h3;Transforming growth factor-beta-induced protein ig-h3
UNIProt ID:
Q15582

References

  • https://pubs.rsc.org/en/content/articlehtml/2020/fo/c9fo02521a