MICA Polyclonal Antibody

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Elabscience
Product Code: E-AB-18241
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-18241-20uL20uL£125.00
Quantity:
E-AB-18241-60uL60uL£172.00
Quantity:
E-AB-18241-120uL120uL£237.00
Quantity:
E-AB-18241-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using MICA Polyclonal Antibody at dilution of 1:60(?200)
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using MICA Polyclonal Antibody at dilution of 1:60(?200)

Documents

Further Information

Abbreviation:
MICA
Background:
This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human MICA
Purification method:
Antigen affinity purification
Target Synonym:
HLA class I antigen;FLJ36918;FLJ60820;MGC111087;MGC21250;MHC class I chain related gene A protein;MHC class I chain related protein A;MHC class I chain related protein A HLA B HLA C;MHC class I polypeptide related sequence A;MHC class I polypeptide-related sequence A;MHC class I related protein;MIC A;MIC-A;micA;MICA;OTTHUMP00000029088;OTTHUMP00000044528;OTTHUMP00000165170;OTTHUMP00000165172;PERB11.1;Stress inducible class I homolog
UNIProt ID:
Q29983