TTR Polyclonal Antibody

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Elabscience
Product Code: E-AB-18211
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-18211-20uL20uL£125.00
Quantity:
E-AB-18211-60uL60uL£172.00
Quantity:
E-AB-18211-120uL120uL£237.00
Quantity:
E-AB-18211-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TTR Polyclonal Antibody at dilution of 1:50(?200)
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Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TTR Polyclonal Antibody at dilution of 1:50(?200)
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TTR Polyclonal Antibody at dilution of 1:50(?200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TTR Polyclonal Antibody at dilution of 1:50(?200)

Documents

Further Information

Abbreviation:
TTR
Background:
Transthyretin (TTR) is a plasma transport protein for thyroxine and retinol,through the association with retinol-binding protein. It is a homotetrameric protein synthesized mainly in liver,choroid plexus,retinal pigment epithelium,and pancreas.Within the CNS,TTR is the only known protein synthesized solely by the choroid plexus. Mutant and wildtype TTR give rise to various forms of amyloid deposition (amyloidosis). Defects in TTR are the cause of amyloidosis transthyretin-related (AMYL-TTR),hyperthyroxinemia dystransthyretinemic euthyroidal (HTDE) and carpal tunnel syndrome type 1 (CTS1). In addition,positive immunostaining for TTR has been reported as a sensitive diagnostic marker of choroid plexus tumors. (22103483)
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
16 kDa
Concentration:
0.72 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human TTR
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
Amyloid polyneuropathy;Amyloidosis I;ATTR;Carpal tunnel syndrome 1;CTS;CTS1;Dysprealbuminemic euthyroidal hyperthyroxinemia;Dystransthyretinemic hyperthyroxinemia;Epididymis luminal protein 111;HEL111;HsT2651;PALB;Prealbumin amyloidosis type I;Prealbumin;Prealbumin Thyroxine-binding;Senile systemic amyloidosis;TBPA;Thyroxine binding prealbumin;Transthyretin;TTHY;TTR;TTR protein
UNIProt ID:
P02766