KIAA0556 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-18186-20uL | 20uL | £125.00 |
Quantity:
| E-AB-18186-60uL | 60uL | £172.00 |
Quantity:
| E-AB-18186-120uL | 120uL | £237.00 |
Quantity:
| E-AB-18186-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
KIAA0556
Background:
This gene encodes a novel, evolutionarily conserved, ciliary protein. In human hTERT-RPE1 cells, the protein is found at the base of cilia, decorating the ciliary axoneme, and enriched at the ciliary tip. The protein binds to microtubules in vitro and regulates their stability when it is overexpressed. A null mutation in this gene has been associated with Joubert syndrome, a recessive disorder that is characterized by a distinctive mid-hindbrain and cerebellar malformation and is also often associated with wider ciliopathy symptoms. Consistently, in a serum-starvation ciliogenesis assay, human fibroblast cells derived from patients with the mutation display a reduced number of ciliated cells with abnormally long cilia.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.96 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human KIAA0556
Purification method:
Antigen affinity purification
Target Synonym:
K0556;KIAA0556;Uncharacterized protein KIAA0556
UNIProt ID:
O60303