G6PC Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-18169-20uL | 20uL | £125.00 |
Quantity:
| E-AB-18169-60uL | 60uL | £172.00 |
Quantity:
| E-AB-18169-120uL | 120uL | £237.00 |
Quantity:
| E-AB-18169-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
G6PC
Background:
Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.44 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human G6PC
Purification method:
Antigen affinity purification
Target Synonym:
AW107337;G-6-Pase;G6Pase;G6Pase-alpha;g6pc;G6PC;G6PT;Glucose-6-phosphatase alpha;Glucose-6-phosphatase;GSD1;GSD1a;MGC163350;MGC93613;RP23-281C18.19
UNIProt ID:
P35575