ITPR2 Polyclonal Antibody

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Elabscience
Product Code: E-AB-18139
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-18139-20uL20uL£125.00
Quantity:
E-AB-18139-60uL60uL£172.00
Quantity:
E-AB-18139-120uL120uL£237.00
Quantity:
E-AB-18139-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human tonsil tissue using ITPR2 Polyclonal Antibody at dilution of 1:65(?200)
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Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ITPR2 Polyclonal Antibody at dilution of 1:65(?200)
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Immunohistochemistry of paraffin-embedded Human tonsil tissue using ITPR2 Polyclonal Antibody at dilution of 1:65(?200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ITPR2 Polyclonal Antibody at dilution of 1:65(?200)

Documents

Further Information

Abbreviation:
ITPR2
Background:
Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.86 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human ITPR2
Purification method:
Antigen affinity purification
Target Synonym:
4;5-trisphosphate receptor;Inositol 1 4 5 trisphosphate receptor type 2;Inositol 1;4;5-trisphosphate receptor type 2;Inositol 145 trisphosphate receptor type 2;InsP3 R2;InsP3R2;IP3 R2;IP3 receptor;IP3 receptor isoform 2;IP3R 2;IP3R2;ITPR 2;Itpr2;ITPR2;Type 2 inositol 1 4 5 trisphosphate receptor;Type 2 inositol 1;Type 2 inositol 145 trisphosphate receptor;Type 2 InsP3 receptor
UNIProt ID:
Q14571