HLA-DPA1 Polyclonal Antibody

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Elabscience
Product Code: E-AB-18082
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-18082-20uL20uL£125.00
Quantity:
E-AB-18082-60uL60uL£172.00
Quantity:
E-AB-18082-120uL120uL£237.00
Quantity:
E-AB-18082-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of Raji cell Human spleen tissue lysates using HLA-DPA1 Polyclonal Antibody at dilution of 1:400
2 / 2
Immunohistochemistry of paraffin-embedded Human tonsil tissue using HLA-DPA1 Polyclonal Antibody at dilution of 1:35(?200)
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Western blot analysis of Raji cell Human spleen tissue lysates using HLA-DPA1 Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human tonsil tissue using HLA-DPA1 Polyclonal Antibody at dilution of 1:35(?200)

Documents

Further Information

Abbreviation:
HLA-DPA1
Background:
HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
29 kDa
Concentration:
0.96 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human HLA-DPA1
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
DP(W3);DP(W4);HLA class II histocompatibility antigen DP alpha 1 chain;HLA class II histocompatibility antigen DP alpha chain ;HLA DP1A;HLA DPA 1;HLA SB alpha chain;HLADP;HLADPA1 ;HLASB;HLASB histocompatibility type;Human MHC class II HLA SB alpha gene;Major histocompatibility complex class II DP alpha 1;MHC class II antigen;MHC class II DP3 alpha;MHC class II DPA1;MHC class II HLA DPA1 antigen;PLT1;Primed lymphocyte test 1
UNIProt ID:
P20036