GSTM2 Polyclonal Antibody

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Elabscience
Product Code: E-AB-18062
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-18062-20uL20uL£125.00
Quantity:
E-AB-18062-60uL60uL£172.00
Quantity:
E-AB-18062-120uL120uL£237.00
Quantity:
E-AB-18062-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human lung cancer tissue using GSTM2 Polyclonal Antibody at dilution of 1:50(?200)
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Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using GSTM2 Polyclonal Antibody at dilution of 1:50(?200)
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Immunohistochemistry of paraffin-embedded Human lung cancer tissue using GSTM2 Polyclonal Antibody at dilution of 1:50(?200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using GSTM2 Polyclonal Antibody at dilution of 1:50(?200)

Documents

Further Information

Abbreviation:
GSTM2
Background:
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.44 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human GSTM2
Purification method:
Antigen affinity purification
Target Synonym:
Glutathione S alkyltransferase M2;Glutathione S aralkyltransferase M2;Glutathione S aryltransferase M2;Glutathione S transferase 4;Glutathione S transferase M1;Glutathione S transferase M2 (muscle);Glutathione S transferase Mu 2 (muscle);Glutathione S transferase Mu 2;Glutathione S-transferase Mu 2;GST class mu 2;GST class-mu 2;GST muscle;GST4;GSTM;GSTM2;GSTM2-2;GSTM2;GTHMUS;MGC117303;S (hydroxyalkyl)glutathione lyase M2
UNIProt ID:
P28161