HLA-G Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-18031-20uL | 20uL | £125.00 |
Quantity:
| E-AB-18031-60uL | 60uL | £172.00 |
Quantity:
| E-AB-18031-120uL | 120uL | £237.00 |
Quantity:
| E-AB-18031-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
HLA-G
Background:
Human major histocompatibility complex (MHC) antigens,also referred to as human leukocyte antigens (HLA),are encoded by genes located on the short arm of chromosome 6 (6p21.3). HLA-G is a non-classical MHC class I molecule with multiple immunoregulatory properties. HLA-G exhibits a restricted pattern of expression that includes placental extravillous trophoblasts at the maternal-fetal interface,where it abolishes maternal immune cell activity against fetus and establishes immune tolerance. Aberrant expression of HLA-G has been found in a variety of human neoplastic diseases. It plays an important role in the escape of tumor cells from immunosurveillance.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.26 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human HLA-G
Purification method:
Antigen affinity purification
Target Synonym:
B2 microglobulin;DADB-15K14.8;HLA 6.0;HLA class I histocompatibility antigen alpha chain G;HLA class I histocompatibility antigen;alpha chain G;HLA class I molecule;HLA G;HLA G antigen;HLA G histocompatibility antigen class I G;HLA G3;HLA-G;HLA-G histocompatibility antigen;class I;HLA60;HLAG;HLAG;Major histocompatibility complex class I G;MHC class I antigen;MHC class I antigen G;MHC G;T-cell A locus;TCA
UNIProt ID:
P17693
References
- https://www.nature.com/articles/s41598-022-12870-6