KDM2A Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-17949-20uL | 20uL | £125.00 |
Quantity:
| E-AB-17949-60uL | 60uL | £172.00 |
Quantity:
| E-AB-17949-120uL | 120uL | £237.00 |
Quantity:
| E-AB-17949-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
KDM2A
Background:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.62 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human KDM2A
Purification method:
Antigen affinity purification
Target Synonym:
[Histone-H3]-lysine-36 demethylase 1A;CXXC-type zinc finger protein 8;CXXC8;F box / LRR repeat protein 11;F box and leucine rich repeat protein 11;F box protein FBL7;F-box and leucine-rich repeat protein 11;F-box protein FBL7;F-box protein Lilina;F-box/LRR-repeat protein 11;FBL11;FBL7;FBXL11;JHDM1A;JmjC domain-containing histone demethylation protein 1A;Jumonji C domain containing histone demethylase 1A ;kdm2a;KDM2A;LILINA;Lysine (K) specific demethylase 2A;Lysine-specific demethylase 2A
UNIProt ID:
Q9Y2K7