DMGDH Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-17889-20uL | 20uL | £125.00 |
Quantity:
| E-AB-17889-60uL | 60uL | £172.00 |
Quantity:
| E-AB-17889-120uL | 120uL | £237.00 |
Quantity:
| E-AB-17889-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
DMGDH
Background:
This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
97 kDa
Concentration:
2.1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human DMGDH
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
Dimethylglycine dehydrogenase;Dimethylglycine dehydrogenase;mitochondrial;Dmgdh;M2GD;ME2GLYDH;mitochondrial
UNIProt ID:
Q9UI17