LPIN1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-17873-20uL | 20uL | £125.00 |
Quantity:
| E-AB-17873-60uL | 60uL | £172.00 |
Quantity:
| E-AB-17873-120uL | 120uL | £237.00 |
Quantity:
| E-AB-17873-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
LPIN1
Background:
This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
99 kDa
Concentration:
1.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human LPIN1
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
EC=3.1.3.4;KIAA0188 ;Lipin-1;Lpin1;LPIN1;PAP1;Phosphatidate phosphatase LPIN1
UNIProt ID:
Q14693