CCL5 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-17864-20uL | 20uL | £125.00 |
Quantity:
| E-AB-17864-60uL | 60uL | £172.00 |
Quantity:
| E-AB-17864-120uL | 120uL | £237.00 |
Quantity:
| E-AB-17864-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
CCL5
Background:
This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human CCL5
Purification method:
Antigen affinity purification
Target Synonym:
Beta chemokine RANTES;Beta chemokine RANTES precursor;C C motif chemokine 5;CCL 5;CCL5;CCL5;Chemokine (C C motif) ligand 5;Chemokine CC Motif Ligand 5;D17S136E;EoCP;Eosinophil chemotactic cytokine;MGC17164;RANTES(4-68);Regulated upon activation normally T expressed and presumably secreted;SCYA 5;SCYA5;SIS delta;SIS-delta;SISd;Small inducible cytokine A5 (RANTES);Small inducible cytokine A5;Small inducible cytokine subfamily A (Cys Cys) member 5;Small-inducible cytokine A5;T cell specific protein p288 ;T cell specific RANTES protein;T cell-specific protein P228;T-cell-specific protein RANTES;TCP 228;TCP228
UNIProt ID:
P13501