CD1B Polyclonal Antibody
Code | Size | Price |
---|
E-AB-17775-20uL | 20uL | £125.00 |
Quantity:
E-AB-17775-60uL | 60uL | £172.00 |
Quantity:
E-AB-17775-120uL | 120uL | £237.00 |
Quantity:
E-AB-17775-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Images
Further Information
Abbreviation:
CD1B
Background:
CD1B (CD1b Molecule) is a Protein Coding gene. Diseases associated with CD1B include Mycobacterium Malmoense and Immune System Organ Benign Neoplasm. Among its related pathways are Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell and Innate Immune System. GO annotations related to this gene include beta-2-microglobulin binding and endogenous lipid antigen binding. An important paralog of this gene is CD1C.This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human CD1B
Purification method:
Antigen affinity purification
Target Synonym:
A1 domain;CD1;CD1A;CD1b;CD1b antigen;CD1B antigen b polypeptide;CD1b molecule;CD1B;Cortical thymocyte antigen CD1A;Cortical thymocyte antigen CD1B;Differentiation antigen CD1 alpha 3;hTa1 thymocyte antigen;Ly38;Ly38;T cell surface glycoprotein CD1a;MGC125990;MGC125991;R1;T-cell surface glycoprotein CD1b;T6/Leu6;Thymocite antigen CD1B
UNIProt ID:
P29016