CYP11B2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-17738-20uL | 20uL | £125.00 |
Quantity:
| E-AB-17738-60uL | 60uL | £172.00 |
Quantity:
| E-AB-17738-120uL | 120uL | £237.00 |
Quantity:
| E-AB-17738-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
CYP11B2
Background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
58 kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human CYP11B2
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
ALDOS;Aldosterone synthase;Aldosterone-synthesizing enzyme;C11B2;CYP11B2;CYPXIB2;Cytochrome P-450Aldo;Cytochrome P-450C18;Cytochrome P450 11B2;Cytochrome P450 11B2; mitochondrial;mitochondrial;P-450Aldo;P-450C18;Steroid 18-hydroxylase
UNIProt ID:
P19099