CDC123 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-17737-20uL | 20uL | £125.00 |
Quantity:
| E-AB-17737-60uL | 60uL | £172.00 |
Quantity:
| E-AB-17737-120uL | 120uL | £237.00 |
Quantity:
| E-AB-17737-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
CDC123
Background:
The eukaryotic cell division cycle consists of a number of gene-controlled sequences that involve cyclin dependent kinases (Cdks) and cell division control (Cdc) proteins. Cdc123 (Cell division cycle protein 123), also known as D123, is a 336 amino acid cytoplasmic protein that is involved in cell cycle control. Widely expressed with high expression in thymus, spleen, ovary, testis, small intestine and leukocytes, Cdc123 functions to destabilize Chfr (checkpoint with forkhead and ring finger domain) proteins which, when accumulated, block the G to S phase transition. Cdc123 prevents the Chfr proteins from collecting in the cell, thereby allowing the cell to enter the S phase. Due to its role in cell cycle control, Cdc123 is thought to be a basal marker for luminal breast cancers.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
39 kDa
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human CDC123
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
C10orf7;CD123;CDC123;Cell division cycle 123;Cell division cycle 123 homolog;Cell division cycle protein 123 homolog;D123;HT 1080;HT-1080;Protein D123;PZ32
UNIProt ID:
O75794