Recombinant Rhesus macaque B7-H4/VTCN1 Protein (His Tag)
| Code | Size | Price |
|---|
| PKSQ050083-10ug | 10ug | £150.00 |
Quantity:
| PKSQ050083-50ug | 50ug | £244.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Monkey
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Further Information
Abbreviation:
B7-H4;VTCN1
Accession:
F7B770
Activity:
Immobilized Human GFRA1-His(Cat: PKSH033670) at 0.5ug/ml(100 ul/well) can bind Human GDNF. The ED50 of GDNF is 14.73ug/ml.
Background:
B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. It also involved in promoting epithelial cell transformation.
Calculated MW:
26.4 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
40-60 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Phe29-Ala258
Target Synonym:
B7S1;B7x;Vtcn1;B7h.5;B7-H4;B7H4T-cell costimulatory molecule B7x;B7S1VCTN1;B7XPRO1291;FLJ22418;Immune costimulatory protein B7-H4;Protein B7S1;T cell costimulatory molecule B7x;V-set domain containing T cell activation inhibitor 1;V-set domain-containing T-cell activation inhibitor 1
UNIProt ID:
F7B770