Recombinant Macaca nemestrina PCSK9/Proprotein Convertase 9 Protein (His Tag)
| Code | Size | Price |
|---|
| PKSQ050064-10ug | 10ug | £256.00 |
Quantity:
| PKSQ050064-50ug | 50ug | £553.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Monkey
Regulatory Status: RUO
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt store it immediately at < -20°C.
Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Further Information
Abbreviation:
PCSK9;Proprotein Convertase 9
Accession:
A8T662
Background:
Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. PCSK9 also plays a role in the neural development.
Calculated MW:
14&59 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Supplied as a 0.2 um filtered solution of 50mM HEPES,150mM NaCl,20%Glycerol,pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
18&70 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Gln31-Gln152&Ser153-Gln692
Target Synonym:
Proprotein Convertase Subtilisin/Kexin Type 9;Proprotein Convertase 9;PC9;Subtilisin/Kexin-Like Protease PC9;PCSK9
UNIProt ID:
A8T662