Recombinant Cynomolgus PD-L2/B7-DC/CD273 Protein (Fc Tag)
| Code | Size | Price |
|---|
| PKSQ050032-10ug | 10ug | £180.00 |
Quantity:
| PKSQ050032-50ug | 50ug | £378.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Monkey
Regulatory Status: RUO
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Further Information
Abbreviation:
PD-L2;B7-DC;CD273
Accession:
A4GW30
Background:
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart, placenta, pancreas, lung and liver; it is weakly expressed in the spleen, lymph nodes, and thymus. PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Calculated MW:
49.5 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS,pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-Fc
ObservedMW:
60-90 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Leu20-Pro219
Target Synonym:
Programmed Cell Death 1 Ligand 2;PD-1 Ligand 2;PD-L2;PDCD1 Ligand 2;Programmed Death Ligand 2;Butyrophilin B7-DC;B7-DC;CD273;PDCD1LG2;B7DC;CD273;PDCD1L2;PDL2
UNIProt ID:
A4GW30