Recombinant Mouse ST6GALNAC2 Protein (His Tag)
| Code | Size | Price |
|---|
| PKSM041361-10ug | 10ug | £297.00 |
Quantity:
| PKSM041361-50ug | 50ug | £498.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Regulatory Status: RUO
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt store it immediately at < -20°C.
Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Further Information
Abbreviation:
ST6GALNAC2
Accession:
P70277
Background:
Alpha-N-acetylgalactosaminide alpha -2,6-sialyltransferase 2, is a type-II membrane protein localized in the Golgi network and catalyzes 2,6-sialylation of the Tn antigen. Sialyl-Tn antigen is highly expressed in several human carcinomas and is associated with carcinoma aggressiveness and poor prognosis. It has been reported that disregulation of this gene is involved in the pathogenesis of IgA nephropathy, a common kidney disease that occurs when antibody IgA accumulates in kidneys (4). The enzyme may also be used to synthesize a cancer vaccine.
Calculated MW:
40.4 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Supplied as a 0.2 um filtered solution of 50mMTris,150mMNaCl,pH7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
45 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ser28-Arg373
Target Synonym:
Gal-beta-1;3-GalNAc alpha-2;6-sialyltransferase;GalNAc alpha-2;6-sialyltransferase II;ST6GalNAc II;Sialyltransferase 7B;SIAT7-B;II;Siat7;Siat7b;ST6GalNAc
UNIProt ID:
P70277