Recombinant Mouse Pleiotrophin/PTN/HB-GAM Protein (His Tag)
| Code | Size | Price |
|---|
| PKSM041292-10ug | 10ug | £155.00 |
Quantity:
| PKSM041292-50ug | 50ug | £287.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Regulatory Status: RUO
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Further Information
Abbreviation:
Pleiotrophin;PTN;HB-GAM
Accession:
P63089
Background:
Pleiotrophin (PTN) is an secreted, strongly heparinbinding,developmentally regulated cytokine. PTN and midkine share50% amino acid (aa) sequence identity, share some functions, and constitute a family. PTN is a highly conserved protein human, mouse, rat, canine, porcine, equine and bovine PTN share 98% aa sequence identity orgreater. During development, PTN is involved in development of brain, bone, and organs undergoing branching morphogenesis. PTN causes PTPRB dimerization and inactivates its phosphatase activity, which allows increased tyrosine phosphorylation of its substrates. Increased expression of PTN is correlated withneuronal development or stresses such as brain ischemia and Parkinson?s disease.
Calculated MW:
16.1 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
18 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Gly33-Asp168
Target Synonym:
Pleiotrophin;PTN;Heparin-binding brain mitogen;HBBM;Heparin-binding growth factor 8;HBGF-8;Osteoblast-specific factor 1;OSF-1;HARP;HB-GAM;HBBN;HBNF;OSF;Osf-1;Osf1
UNIProt ID:
P63089