Recombinant Mouse CD73/NT5E Protein (His Tag)

Elabscience
Product Code: PKSM041234
Product Group: Recombinant Proteins
Supplier: Elabscience
CodeSizePrice
PKSM041234-10ug10ug£256.00
Quantity:
PKSM041234-50ug50ug£553.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Regulatory Status: RUO
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt store it immediately at < -20°C.
Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

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Further Information

Abbreviation:
CD73;NT5E
Accession:
NP_035981.1
Background:
Mouse CD73 is a glycosyl phosphatidylinositol (GPI) anchored membrane protein that belongs to the 5'-nucleotidase family. CD73 is an ecto 5'Nucleotidase expressed by most cell types. CD73 hydrolyzes extracellular nucleotides into membrane permeable nucleosides. CD73 is one of several enzymes responsible for the production of extracellular adenosine, a signaling molecule that is involved in responses to inflammation and tissue injury. CD73 is a lymphocyte maturation marker that has functions independent of its catalytic activity. CD73 is also a regulator of leukocyte extravasation, a function that requires its 5'Nucleotidase activity.CD73 has also been reported to regulate expression of pro-inflammatory molecules in mouse endothelium.
Calculated MW:
58.8 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 120mM NaCl,4mM CaCl2, 20% Glycerol, pH 7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
60 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Trp29-Phe550
Target Synonym:
5'-nucleotidase;Ecto-5'-nucleotidase;CD73;5'-NT;AI447961;eNT;NT;Nt5 Protein